Only two NFL teams have clinched a playoff berth after 15 weeks, showing how tightly the league is bunched at the top. What's in store this week?
RotoWire used ChatGPT to see what the AI tool would predict the results to be for each game during NFL Week 16. We asked for 10 simulations of each matchup, with game scores, using NFL rosters and available injury information as of Dec. 16. After that, we averaged the margin of victory for each matchup. RotoWire.com, as part of our NFL betting coverage, got these simulated results:
ChatGPT Predicts NFL Week 16 Results
Matchup | Result | Visitors Avg. MOV | Home Avg.MOV |
LAR at SEA | 5-5 | 5.0 | 4.4 |
PHI at WAS |
| 9.4 | 1.7 |
GB at CHI |
| 7.7 | 3.0 |
BUF at CLE |
| 8.0 | 3.0 |
CIN at MIA | 5-5 | 5.0 | 4.2 |
KC at TEN |
| 2.7 | 8.4 |
LAC at DAL | 5-5 | 3.2 | 3.4 |
MIN at NYG |
| 9.9 | 1.7 |
NYJ at NO |
| 2.8 | 7.3 |
TB at CAR |
| 5.4 | 4.7 |
ATL at ARI | 5-5 | 3.4 | 4.8 |
JAX at DEN |
| 4.8 | 5.3 |
LV at HOU |
| 2.0 | 7.8 |
PIT at DET |
| 3.0 | 8.4 |
NE at BAL |
| 10.2 | 2.5 |
SF at IND |
| 5.7 | 5.0 |
Eagles 7-3
Bills 7-3
Titans 7-3
Vikings 7-3
Saints 6-4
Buccaneers 7-3
Broncos 6-4
Texans 7-3
Lions 7-3
Patriots 8-2
49ers 6-4Which Week 16 Games Are Too Close To Call?
ChatGPT projects a competitive week as playoff races take shape and NFL Week 16 odds reflect this. Only two games (Bills -10 at Browns and Texans -14 vs. Raiders) have a point spread of more than a touchdown as of Dec. 16.
Four games are projected as 5-5 splits over 10 simulations. The Los Angeles Chargers at Dallas Cowboys has playoff implications for L.A., while Dallas clings to extremely slim hopes. There are two games between teams that have been eliminated from playoff contention – the Cincinnati Bengals at Miami Dolphins and Atlanta Falcons at Arizona Cardinals.
But the best game this week at top sports betting apps is the first one: Thursday's NFC West tilt with the 
Los Angeles Rams traveling to Seattle.
The Seahawks are the No. 5 seed in the NFC playoff picture going in, but they can vault to No. 1 by defeating their division rivals in what is sure to be a deafening atmosphere at Lumen Field.
The Rams hold the top seed in the conference and are the only team in the NFC that has clinched a playoff spot. Coach Sean McVay's team defeated the visiting Seahawks 21-19 on Nov. 16. L.A. is second in total offense at 383.6 yards per game, behind only Dallas. Quarterback Matthew Stafford, at age 37, could be headed for his first Most Valuable Player honor. He's the current NFL MVP odds favorite in a season where he has thrown for 3,722 yards, a league-high 37 touchdowns and just five interceptions.
But the 
Seahawks have the same 11-3 record as Los Angeles, and Seattle has home-field advantage this time. Coach Mike Macdonald's team is No. 4 in total defense (allowing 283 ypg) and ninth in offense (350.6 ypg). Only two other teams rank in the top 10 in both total offense and total defense.
The best price on the Seahawks as of Tuesday afternoon is at DraftKings Sportsbook, where Seattle is a 1.5-point underdog. The Seahawks have won four in a row and eight of their past nine, with the pervious meeting against the Rams being their only loss.
Those wishing to wager on the Rams might want to look at BetRivers Sportsbook, which had the game listed as a pick-'em proposition. Both teams are -112 on the moneyline with that operator.
Are There Any Other Projected Close Games In Week 16?
Yes, four more games are projected with 6-4 splits after 10 AI simulations: Packers at Bears, Jaguars at Broncos, the Monday matchup with the 49ers visiting the Colts, and the Jets at Saints game that has no bearing on the standings but might change NFL Draft odds.
The 
Bears hold the NFC's No. 2 seed going into this weekend, leading a topsy-turvy North division race.
But Green Bay, half a game behind, is still a slight favorite with BetMGM Sportsbook to win the division at -105 odds. The Packers face their rivals on Saturday (8:20 p.m., FOX) with both teams getting one less day of rest than normal.
The 
Packers won the first meeting, 28-21, on Dec. 7 at Lambeau Field. They now head into Soldier Field with a chance to pull off a head-to-head sweep and a half-game division lead.
Week 16 NFL AI Projections Q&A
Q: How did ChatGPT simulate NFL Week 16 games?
A: RotoWire ran 10 simulations for every Week 16 matchup using ChatGPT, with rosters updated as of Dec. 16, 2025. Each game produced projected scores, a winner, and a calculated average margin of victory (MOV). This allowed us to compare not only who wins most often but also how decisively they win.
Q: Which teams dominated the ChatGPT simulations?
A: There were no matchups with one team sweeping another over 10 simulations. The New England Patriots (vs Baltimore Ravens) had the strongest projected results, with ChatGPT projecting the Patriots to win 80% of the simulated games.
Q: What were the closest or most balanced matchups in the simulations?
A: Many teams had close matchups for Week 16, according to ChatGPT. The AI tool projected the following matchups to be a toss-up, splitting 5-5: Los Angeles Rams at Seattle Seahawks, Cincinnati Bengals at Miami Dolphins, Los Angeles Chargers at Dallas Cowboys and Atlanta Falcons at Arizona Cardinals.
