Injury news in soccer is notoriously sketchy, so while the below information should be used as a guide, always check the confirmed lineups before every match.
Note: this column is updated throughout the week as injury news is released.
v. 
ESPN Wide World of Sports Complex
Friday, October 16 at 7:00 p.m. EDT
Orlando City SC
Suspended:Kaka, Brek Shea
Out:Conor Donovan (knee), Harrison Heath (kneecap), Kevin Molino (knee)
Doubtful:Earl Edwards, Jr. (knee), Seb Hines (shoulder)
Questionable:Corey Ashe (undisclosed), Rafael Ramos (head), Tommy Redding (head)
New York City FC
Suspended:RJ Allen, Jason Hernandez, Sebastian Velasquez
Out:George John (knee), Tony Taylor (knee)
Doubtful:Connor Brandt (hernia), Javier Calle (hamstring)
Questionable:Shay Facey (knee), Iraola (calf)
v. 
Avaya Stadium
Friday, October 16 at 11:00 p.m. EDT
San Jose Earthquakes
Suspended:Victor Bernardez, Marc Pelosi
Out:Innocent (knee), Steven Lenhart (knee), Jordan Stewart (Achilles)
Doubtful:Jean-Baptiste Pierazzi (foot), Paulo Renato (quad), Mark Sherrod (concussion), Khari Stephenson (calf)
Sporting Kansas City
Out:Roger Espinoza (foot), Ike Opara (Achilles)
v. 
BMO Field
Saturday, October 17 at 2:00 p.m. EDT
Toronto FC
Suspended:Jozy Altidore
Out:Mark Bloom (quad)
Questionable:Daniel Lovitz (foot), Clement Simonin (knee)
Columbus Crew
Out:Sagi Lev-Ari (knee)
Questionable:Chad Barson (ankle), Jack McInerney (hamstring), Gaston Sauro (concussion), Tony Tchani (groin)
v. 
Gillette Stadium
Saturday, October 17 at 7:30 p.m. EDT
New England Revolution
Suspended:Teal Bunbury
Out:Darrius Barnes (knee)
Montreal Impact
Suspended:Laurent Ciman
Out:Cameron Porter (knee), Andres Romero (knee)
Doubtful:Kenny Cooper (knee), Adrian Lopez (knee)
Questionable:Kyle Bekker (undisclosed), Justin Mapp (toe)
v. 
Rio Tinto Stadium
Saturday, October 17 at 9:30 p.m. EDT
Real Salt Lake
Suspension:Jamison Olave
Out:Chris Schuler (foot)
FC Dallas
Doubtful:Stephen Keel (quad), Bakary Soumare (concussion)
Questionable:Kellyn Acosta (hamstring)
v. 
RFK Memorial Stadium
Sunday, October 18 at 2:00 p.m. EDT
D.C. United
Out:Chris Korb (knee)
Doubtful:Davy Arnaud (concussion)
Chicago Fire
Out:Adailton (abdomen), Eric Gehrig (heel), Sean Johnson (shoulder)
Questionable:Ty Harden (thigh)
v. 
Red Bull Arena
Sunday, October 18 at 3:00 p.m. EDT
New York Red Bulls
Suspension:Matt Miazga
Out:Chris Duvall (leg), Roy Miller (knee)
Questionable:Anatole Abang (hamstring)
Philadelphia Union
Out:Maurice Edu (hernia)
Doubtful:Jimmy McLaughlin (appendix), Brian Sylvestre (knee)
Questionable:Fred (groin)
v. 
BBVA Compass Stadium
Sunday, October 18 at 5:00 p.m. EDT
Houston Dynamo
Suspension:Raul Rodriguez
Out:Jermaine Taylor (quad)
Questionable:Kofi Sarkodie (knee)
Seattle Sounders
Out:Roman Torres (knee)
Doubtful:Andres Correa (thigh)
Questionable:Andy Craven (knee), Oniel Fisher (hamstring), Damion Lowe (hip), Chad Marshall (undisclosed)
v. 
StubHub Center
Sunday, October 18 at 7:00 p.m. EDT
Los Angeles Galaxy
Out:Brian Perk (ankle)
Questionable:Giovani dos Santos (knock), Todd Dunivant (foot), Baggio Husidic (leg), Bradford Jamieson (concussion), Robbie Rogers (hip)
Portland Timbers
Out:Ben Zemanski (knee)
Questionable:Jack Jewsbury (foot), Will Johnson (leg)
