New York Giants vs San Francisco 49ers Odds, Week 9, 2025

#1 C

Jake Brendel: Sidelined again

Oct 31st

Brendel (hamstring) was ruled out ahead of Sunday's matchup against the Giants,Jennifer Lee Chan of NBC Sports Bay Area reports.

#1 DT2

Jordan Elliott: Not traveling with team

Oct 31st

Elliott (ankle), who is questionable for Sunday's matchup against the Giants, is not traveling with the 49ers to New York on Friday due to personal reasons, Vic Tafur of The Athletic reports.

#1 SCB

Upton Stout: Cleared for Week 9

Oct 31st

Stout (shoulder) has no injury designation ahead of Sunday's game against the Giants.

#2 LDE

Yetur Gross-Matos: Remains out for Week 9

Oct 31st

Gross-Matos (knee/hamstring) has been ruled out for Sunday's game against the Giants, Jennifer Lee Chan of NBC Sports Bay Area reports.

#1 LDE

Bryce Huff: Out for Week 9

Oct 31st

Huff (hamstring) has been ruled out for Sunday's game against the Giants, Jennifer Lee Chan of NBC Sports Bay Area reports.

#1 WLB

Dee Winters: Questionable for Week 9

Oct 31st

Winters (knee) is listed as questionable for Sunday's game against the Giants, Jennifer Lee Chan of NBC Sports Bay Area reports.

#2 WR

Ricky Pearsall: Ruled out again

Oct 31st

Pearsall (knee) won't play Sunday against the Giants, Cam Inman of The San Jose Mercury News reports.

#2 QB

Mac Jones: Getting another start

Oct 31st

Jones will start Sunday's game at the Giants, Matt Maiocco of NBC Sports Bay Area reports.

#1 QB

Brock Purdy: Won't start, deemed questionable

Oct 31st

Purdy (toe) won't start Sunday's game against the Giants but is listed as questionable to be available in a backup capacity, Matt Maiocco of NBC Sports Bay Area reports.

#1 LCB

Renardo Green: Posts eight stops vs. Houston

Oct 30th

Green registered eight tackles (four solo) during the 49ers' 26-15 loss to the Texans on Sunday.

#1 RCB

Deommodore Lenoir: Haults in first INT of 2025

Oct 30th

Lenoir registered three tackles (two solo) and one interception during the 49ers' 26-15 loss to the Texans on Sunday.

#2 RDE

Sam Okuayinonu: Limited in return to practice

Oct 30th

Okuayinonu (ankle) was a limited participant in Thursday's practice, Eric Branch of the San Francisco Chronicle reports.

#2 LT

Spencer Burford: Full participant in practice

Oct 29th

Burford (knee) was a full participant in San Francisco's practice Wednesday, Eric Branch of the San Francisco Chronicle reports.

#2 LG

Ben Bartch: Limited in practice

Oct 29th

Bartch (ankle) was a limited participant in San Francisco's practice Wednesday, David Lombardi of SFStandard.com reports.

#3 TE

Jake Tonges: Scores, but plays just five snaps

Oct 29th

Tonges recorded a two-yard touchdown reception on his lone target while playing five of the 49ers' 48 snaps on offense in Sunday's 26-15 loss to the Texans.

#6 WR

Jordan Watkins: One catch in NFL debut

Oct 29th

Watkins recorded a seven-yard reception on two targets in Sunday's 26-15 loss to the Texans.

#3 RB

Isaac Guerendo: No run on offense this season

Oct 29th

Guerendo played all 10 of his snaps on special teams in Sunday's 26-15 loss to the Texans.

#1 FS

Malik Mustapha: Season-high stops in Week 8 loss

Oct 28th

Mustapha made 12 tackles (six solo) during Sunday's loss to the Texans.

#1 MLB

Tatum Bethune: Logs double-digit stops again

Oct 28th

Bethune made 14 tackles (four solo) during Sunday's loss to the Texans.

#3 RDE

Keion White: Sent to Bay Area

Oct 28th

The 49ers acquired White and a 2026 seventh-round pick from the Patriots on Tuesday in exchange for a 2026 sixth-round pick, Tom Pelissero of NFL Network reports.

#7 WR

Brandon Aiyuk: Unlikely to have practice window opened this week

Oct 27th

Coach Kyle Shanahan said Monday that the 49ers don't intend to designate Aiyuk (knee) to return from the reserve/PUP list Wednesday, Matt Barrows of The Athletic reports.

#5 WR

Skyy Moore: Splits snaps between offense and ST

Oct 27th

Moore failed to collect his only target on offense while returning two kicks for 52 yards in Sunday's 26-15 loss to the Texans.

#4 WR

Demarcus Robinson: Converts two-point attempt Sunday

Oct 27th

Robinson pulled in two of three targets for five yards while catching a successful two-point attempt in Sunday's 26-15 loss to Houston.

#2 RB

Brian Robinson: Limited to two offensive snaps

Oct 27th

Robinson did not record a touch on offense while returning three kicks for 99 yards in Sunday's 26-15 loss to the Texans.

#3 WR

Kendrick Bourne: Solid production on three catches

Oct 26th

Bourne brought in three of four targets for 44 yards in the 49ers' 26-15 loss to the Texans on Sunday.

#1 WR

Jauan Jennings: Under 50 receiving yards in loss

Oct 26th

Jennings brought in four of seven targets for 45 yards in the 49ers' 26-15 loss to the Texans on Sunday.

#1 TE

George Kittle: Commemorates 'holiday' with TD

Oct 26th

Kittle brought in four of five targets for 43 yards and a touchdown in the 49ers' 26-15 loss to the Texans on Sunday.

#1 K

Eddy Pineiro: Quiet day in Week 8 loss

Oct 26th

Pineiro made his lone extra-point try during the 49ers' 26-15 loss to the Texans on Sunday.

#1 RB

Christian McCaffrey: Modest production with 11 touches

Oct 26th

McCaffrey rushed eight times for 25 yards and brought in three of six targets for 43 yards in the 49ers' 26-15 loss to the Texans on Sunday.

#1 SLB

Luke Gifford: Good to go

Oct 26th

Gifford is active for Sunday's game against the Texans.

#2 FS

Marques Sigle: Sees playing time drop in Week 7

Oct 21st

Sigle recorded two tackles (one solo) while playing just 31 percent of San Francisco's defensive snaps in Sunday's 20-10 win over Atlanta.

#2 DT2

Kevin Givens: Good to go Sunday night

Oct 19th

Givens (pectoral) is active for Sunday night's game against the Falcons.

#4 RB

Jordan James: Not playing Sunday night

Oct 19th

James (coach's decision) is inactive for Sunday Night Football against the Falcons.

#2 MLB

Fred Warner: Officially placed on IR

Oct 18th

The 49ers placed Warner (ankle) on injured reserve Saturday.